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Article

Genetic model testing and statistical power in population-based association studies of quantitative traits.

Genetic epidemiology - 1 May 2007

Lettre Guillaume, Lange Christoph, Hirschhorn Joel N

Abstract excerpt

The optimal method for considering different genetic models in association studies is not clear. We compared analytical strategies that use different genetic models to analyze genotype-phenotype information from association studies of quantitative traits in unrelated individuals. We created simulated datasets where the minor alleles are causal with an additive, dominant, or recessive mode of inheritance over a...

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Identifiers

PMID: 17352422
DOI: 10.1002/gepi.20217

Genes

KCNJ11

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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