Article
Ubiquitylation of the acetyltransferase MOF in Drosophila melanogaster.
PloS one - 1 Jan 2017
Schunter Sarah, Villa Raffaella, Flynn Victoria, Heidelberger Jan B, Classen Anne-Kathrin, Beli Petra, Becker Peter B
Abstract excerpt
The nuclear acetyltransferase MOF (KAT8 in mammals) is a subunit of at least two multi-component complexes involved in transcription regulation. In the context of complexes of the 'Non-Specific-Lethal' (NSL) type it controls transcription initiation of many nuclear housekeeping genes and of mitochondrial genes. While this function is conserved in metazoans, MOF has an additional, specific function in Drosophila...
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