Article
Distinct mechanisms mediate X chromosome dosage compensation in Anopheles and Drosophila.
Life science alliance - 1 Sept 2021
Keller Valsecchi Claudia Isabelle, Marois Eric, Basilicata M Felicia, Georgiev Plamen, Akhtar Asifa
Abstract excerpt
Sex chromosomes induce potentially deleterious gene expression imbalances that are frequently corrected by dosage compensation (DC). Three distinct molecular strategies to achieve DC have been previously described in nematodes, fruit flies, and mammals. Is this a consequence of distinct genomes, functional or ecological constraints, or random initial commitment to an evolutionary trajectory? Here, we study DC in...
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