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Article

HIV-1 Nef-mediated inhibition of T cell migration and its molecular determinants.

Journal of leukocyte biology - 1 Nov 2009

Park In-Woo, He Johnny J

Abstract excerpt

Lymphocyte trafficking is a multistep, intricate process and involves a number of host factors such as integrins and chemokine receptors on lymphocytes, adhesion molecules on endothelial cells, and chemokines present in the local microenvironment. Previous studies have shown that HIV-1 Nef inhibits T cell chemotaxis in response to the physiological ligand SDF-1alpha [( 1) ]. In this study, we aimed to gain a...

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Share to Acquired Immunodeficiency Syndrome
Share to Chemotaxis, Leukocyte
Share to Endothelium, Vascular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to nef Gene Products, Human Immunodeficiency Virus

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Source

Identifiers

PMID: 19641037
DOI: 10.1189/jlb.0409261

Genes

CXCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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