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HIV ‐1 Nef: Taking Control of Protein Trafficking

10 May 2016

Abstract excerpt

The Nef protein of the human immunodeficiency virus is a crucial determinant of viral pathogenesis and disease progression. Nef is abundantly expressed early in infection and is thought to optimize the cellular environment for viral replication. Nef controls expression levels of various cell surface molecules that play important roles in immunity and virus life cycle, by directly interfering with the itinerary of...

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PMID: 27161574
DOI: 10.1111/tra.12412

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HIV ‐1 Nef: Taking Control of Protein TraffickingPMID 27161574Read ↗

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