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Article

Caveolae mediate growth factor-induced disassembly of adherens junctions to support tumor cell dissociation.

Molecular biology of the cell - 1 Oct 2009

Orlichenko Lidiya, Weller Shaun G, Cao Hong, Krueger Eugene W, Awoniyi Muyiwa, Beznoussenko Galina, Buccione Roberto, McNiven Mark A

Abstract excerpt

Remodeling of cell-cell contacts through the internalization of adherens junction proteins is an important event during both normal development and the process of tumor cell metastasis. Here we show that the integrity of tumor cell-cell contacts is disrupted after epidermal growth factor (EGF) st...

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Identifiers

PMID: 19641024
DOI: 10.1091/mbc.e08-10-1043
PMCID: PMC2754928

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19641024-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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