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Article

ZEB1 enhances transendothelial migration and represses the epithelial phenotype of prostate cancer cells.

Molecular biology of the cell - 1 Apr 2009

Drake Justin M, Strohbehn Garth, Bair Thomas B, Moreland Jessica G, Henry Michael D

Abstract excerpt

Metastatic colonization involves cancer cell lodgment or adherence in the microvasculature and subsequent migration of those cells across the endothelium into a secondary organ site. To study this process further, we analyzed transendothelial migration of human PC-3 prostate cancer cells in vitro. We isolated a subpopulation of cells, TEM4-18, that crossed an endothelial barrier more efficiently, but...

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Source

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Identifiers

PMID: 19225155
DOI: 10.1091/mbc.e08-10-1076
PMCID: PMC2669028

Genes

ZEB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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