Article

mDia2 formin selectively interacts with catenins and not E-cadherin to regulate Adherens Junction formation

2019-08-01

Abstract excerpt

<h4>Background</h4> Epithelial ovarian cancer (EOC) cells disseminate within the peritoneal cavity, in part, via the peritoneal fluid as single cells, clusters, or spheroids. Initial single cell egress from a tumor can involve disruption of cell-cell adhesions as cells are shed from the primary tumor into the peritoneum. In epithelial cells, Adherens Junctions (AJs) are characterized by homotypic linkage of E-cad...

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Literature Corpus work: ed62113b-83cb-5294-9488-605a84777e63
DOI: 10.1101/721530

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