Article
Bone marrow large B cell lymphoma bearing cyclin D3 expression: clinical, morphologic, immunophenotypic, and genotypic analyses of seven patients.
International journal of hematology - 1 Sept 2009
Watanuki Jyuri, Hatakeyama Kinta, Sonoki Takashi, Tatetsu Hiro, Yoshida Katsuhiko, Fujii Soichiro, Mizutani Minoru, Abo Toru, Kurimoto Miwa, Matsuoka Hiroshi, Matsuno Fumihiko, Nakakuma Hideki
Abstract excerpt
We report seven large B cell lymphoma patients showing the involvement of tumor cells with cyclin D3 (CCND3) expression in bone marrow (BM) at the initial diagnosis. All patients presented with B symptoms, splenomegaly, and anemia/thrombocytopenia lacking hemophagocytosis in the BM. Five of the seven patients had suffered from immunological diseases or cancers. The tumor cells were divided into those with a...
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