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Article

Indolent mantle cell lymphoma with nodal involvement and mutated immunoglobulin heavy chain genes.

Human pathology - 1 Oct 2003

Nodit Laurentia, Bahler David W, Jacobs Samuel A, Locker Joseph, Swerdlow Steven H

Abstract excerpt

Mantle cell lymphoma (MCL) is typically considered an aggressive but incurable neoplasm composed of cyclin D1+ monoclonal B-cells with a t(11;14)(q13;q32) and usually unmutated immunoglobulin (Ig) genes. Although it has been suggested that a more indolent leukemic disorder exists with the same phenotype and genotype but with mutated Ig genes, others have considered these cases to be variants of chronic...

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Share to Chromosomes, Human, Pair 11
Share to Chromosomes, Human, Pair 14

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Rearrangement, B-Lymphocyte, Heavy Chain

Share to Immunoglobulin Heavy Chains

Share to Immunoglobulin Variable Region

Share to Lymph Nodes

Share to Lymphoma, Mantle-Cell

Share to Translocation, Genetic

Source

Identifiers

PMID: 14608537
DOI: 10.1053/s0046-8177(03)00410-6

Genes

CCND1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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