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Article

ID3 mutations are recurrent events in double-hit B-cell lymphomas.

Anticancer research - 1 Nov 2013

Gebauer Niklas, Bernard Veronica, Feller Alfred C, Merz Hartmut

Abstract excerpt

BACKGROUND: Double-hit lymphomas (DHL) with chromosomal rearrangements affecting the avian myelocytomatosis viral oncogene homolog (cMYC) and either the B-cell lymphoma-2 (BCL2) or -6 (BCL6) locus are uncommon neoplasms with an aggressive clinical course and dismal prognosis. Most cases exhibit a phenotype intermediate between diffuse large B-cell lymphoma (DLBCL) and Burkitt lymphoma. Recently mutations...

Read the complete abstract on PubMed

Topics

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Share to Burkitt Lymphoma
Share to Gene Rearrangement
Share to Immunophenotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to In Situ Hybridization, Fluorescence

Share to Lymphoma, Large B-Cell, Diffuse

Share to Proto-Oncogene Proteins c-bcl-2

Share to Proto-Oncogene Proteins c-bcl-6

Share to Proto-Oncogene Proteins c-myc

Source

Identifiers

PMID: 24222112

Genes

BCL2
BCL6

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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