Article
Regulation of the proteasome by neuronal activity and calcium/calmodulin-dependent protein kinase II.
The Journal of biological chemistry - 25 Sept 2009
Djakovic Stevan N, Schwarz Lindsay A, Barylko Barbara, DeMartino George N, Patrick Gentry N
Abstract excerpt
Protein degradation via the ubiquitin proteasome system has been shown to regulate changes in synaptic strength that underlie multiple forms of synaptic plasticity. It is plausible, therefore, that the ubiquitin proteasome system is itself regulated by synaptic activity. By utilizing live-cell im...
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