Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Degree of cross-genotype reactivity of hepatitis C virus-specific CD8+ T cells directed against NS3.

Hepatology (Baltimore, Md.) - 1 Sept 2009

Giugliano Silvia, Oezkan Filiz, Bedrejowski Mathias, Kudla Markus, Reiser Markus, Viazov Sergei, Scherbaum Norbert, Roggendorf Michael, Timm Joerg

Abstract excerpt

UNLABELLED: The inherent sequence diversity of the hepatitis C virus (HCV) with the existence of multiple genotypes that differ up to 20% at the amino acid level represents one of the major obstacles for immune control. Accordingly, immune control of a heterologous virus challenge, particularly a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to CD8-Positive T-Lymphocytes
Share to Cross Reactions
Share to Drug Users

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epitopes

Share to Genotype

Share to Hepacivirus

Share to Hepatitis C, Chronic

Share to Viral Nonstructural Proteins

Source

Identifiers

PMID: 19637188
DOI: 10.1002/hep.23096

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19637188-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Degree of cross-genotype reactivity of hepatitis C virus-specific CD8+ T cells directed against NS3.PMID 19637188Read ↗

The broad assessment of HCV genotypes 1 and 3 antigenic targets reveals limited cross-reactivity with implications for vaccine design.Semantic proximity Read ↗

Impact of sequence variation in a dominant HLA-A*02-restricted epitope in hepatitis C virus on priming and cross-reactivity of CD8+ T cells.Semantic proximity Read ↗

HCV genotype-3a T cell immunity: specificity, function and impact of therapy.Semantic proximity Read ↗

Hepatitis C cross-genotype immunity and implications for vaccine development.Semantic proximity Read ↗

Cross-genotype-specific T-cell responses in acute hepatitis E virus (HEV) infection.Semantic proximity Read ↗

Cross reactive cellular immune response to HCV genotype 1 and 4 antigens among genotype 4 exposed subjects.Semantic proximity Read ↗

Cross-reactivity of hepatitis C virus specific vaccine-induced T cells at immunodominant epitopes.Semantic proximity Read ↗

CD8+ T-Cell Exhaustion Phenotype in Chronic Hepatitis C Virus Infection Is Associated With Epitope Sequence Variation.Semantic proximity Read ↗

Divergent adaptation of hepatitis C virus genotypes 1 and 3 to human leukocyte antigen-restricted immune pressure.Semantic proximity Read ↗

Antigenic variation of core, NS3, and NS5 proteins among genotypes of hepatitis C virus.Semantic proximity Read ↗

Distinct Escape Pathway by Hepatitis C Virus Genotype 1a from a Dominant CD8+ T Cell Response by Selection of Altered Epitope Processing.Semantic proximity Read ↗

Evidence for lack of cross-genotype protection of CD4+ T cell responses during chronic hepatitis C virus infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.