Article
HCV genotype-3a T cell immunity: specificity, function and impact of therapy.
Gut - 1 Nov 2012
Humphreys Isla S, von Delft Annette, Brown Anthony, Hibbert Linda, Collier Jane D, Foster Graham R, Rahman Monira, Christian Annabel, Klenerman Paul, Barnes Eleanor
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) genotype-3a infection is now the dominant strain in South Asia and the UK. Characteristic features include a favourable response to therapy; the reasons for this are unknown but may include distinct genotype-3a-specific T cell immunity. In contrast to genotype-1 infection, T cell immunity to this subtype is poorly defined. OBJECTIVES: The aims of the study were to (1) define...
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