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Article

Cross reactive cellular immune response to HCV genotype 1 and 4 antigens among genotype 4 exposed subjects.

PloS one - 1 Jan 2014

Galal Iman F, Zakaria Zainab, Allam Walaa R, Mahmoud Mohamed A, Ezzat Ahmed R, Osman Ahmed, Waked Imam, Strickland G Thomas, Abdelwahab Sayed F

Abstract excerpt

BACKGROUND: Hepatitis C Virus (HCV) infection is a global health burden particularly in Egypt, where HCV genotype 4a (GT-4a) predominates. The prevention and control of HCV infection will remain a challenge until the development of an effective vaccine that protects against different genotypes. Several HCV GT-1-based vaccines are in different stages of clinical trials, but antigenic differences could make...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 24979366
DOI: 10.1371/journal.pone.0101264
PMCID: PMC4076338

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