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Article

Puralpha and Purbeta collaborate with Sp3 to negatively regulate beta-myosin heavy chain gene expression during skeletal muscle inactivity.

Molecular and cellular biology - 1 Feb 2007

Ji Juan, Tsika Gretchen L, Rindt Hansjörg, Schreiber Kathy L, McCarthy John J, Kelm Robert J, Tsika Richard

Abstract excerpt

Adult skeletal muscle retains the capability of transcriptional reprogramming. This attribute is readily observable in the non-weight-bearing (NWB) soleus muscle, which undergoes a slow-to-fast fiber type transition concurrent with decreased beta-myosin heavy chain (betaMyHC) gene expression. Our previous work showed that Sp3 contributes to decreased betaMyHC gene expression under NWB conditions. In this study,...

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Source

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Identifiers

PMID: 17145772
DOI: 10.1128/MCB.00629-06
PMCID: PMC1800711

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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