Article
Generation of conditional Hoxc8 loss-of-function and Hoxc8-->Hoxc9 replacement alleles in mice.
Genesis (New York, N.Y. : 2000) - 1 Oct 2009
Blackburn Jessica, Rich Melissa, Ghitani Nima, Liu Jeh-Ping
Abstract excerpt
The Hox family of transcription factors are expressed at different domains along the rostrocaudal (R-C) body axis during development. To examine the function of Hoxc8 and Hoxc9 in specific cell types and at different developmental times, we have generated and characterized loxP flanked (floxed) Hoxc8 and Hoxc8-->Hoxc9 replacement alleles of mice, with either GFP or LacZ reporters. Although all four alleles of...
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