Axial and appendicular skeletal transformations, ligament alterations, and motor neuron loss in Hoxc10 mutants.

Abstract excerpt

Vertebrate Hox genes regulate many aspects of embryonic body plan development and patterning. In particular, Hox genes have been shown to regulate regional patterning of the axial and appendicular skeleton and of the central nervous system. We have identified patterning defects resulting from the targeted mutation of Hoxc10, a member of the Hox10 paralogous family. Hoxc10 mutant mice have skeletal transformations...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bone and Bones
• Share to Bone Development