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Article

Direct evidence for a dry molten globule intermediate during the unfolding of a small protein.

Proceedings of the National Academy of Sciences of the United States of America - 28 Jul 2009

Jha Santosh Kumar, Udgaonkar Jayant B

Abstract excerpt

Little is known about how proteins begin to unfold. In particular, how and when water molecules penetrate into the protein interior during unfolding, thereby enabling the dissolution of specific structure, is poorly understood. The hypothesis that the native state expands initially into a dry mol...

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Identifiers

PMID: 19617531
DOI: 10.1073/pnas.0905744106
PMCID: PMC2718347

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-19617531-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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