Article
Evaluation of expression and function of the H+/myo-inositol transporter HMIT.
BMC cell biology - 16 Jul 2009
Di Daniel Elena, Mok Man H S, Mead Emma, Mutinelli Chiara, Zambello Erika, Caberlotto Laura L, Pell Theresa J, Langmead Christopher J, Shah Ajit J, Duddy Graham, Kew James N C, Maycox Peter R
Abstract excerpt
BACKGROUND: The phosphoinositide (PIns) signalling pathway regulates a series of neuronal processes, such as neurotransmitter release, that are thought to be altered in mood disorders. Furthermore, mood-stabilising drugs have been shown to inhibit key enzymes that regulate PIns production and alter neuronal growth cone morphology in an inositol-reversible manner. Here, we describe analyses of expression and...
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