Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans.

Genetics - 1 Jun 2012

Kimata Tsubasa, Tanizawa Yoshinori, Can Yoko, Ikeda Shingo, Kuhara Atsushi, Mori Ikue

Abstract excerpt

Although neurons are highly polarized, how neuronal polarity is generated remains poorly understood. An evolutionarily conserved inositol-producing enzyme myo-inositol monophosphatase (IMPase) is essential for polarized localization of synaptic molecules in Caenorhabditis elegans and can be inhib...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 5'-Nucleotidase
Share to Caenorhabditis elegans
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Lithium Chloride

Share to Phosphatidylinositols

Share to Phospholipase C beta

Share to Phosphoric Monoester Hydrolases

Share to Synapses

Source

Open in PubMed Open full text

Identifiers

PMID: 22446320
DOI: 10.1534/genetics.111.137844
PMCID: PMC3374314

Genes

PIP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-22446320-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Synaptic polarity depends on phosphatidylinositol signaling regulated by myo-inositol monophosphatase in Caenorhabditis elegans.PMID 22446320Read ↗

Inositol polyphosphate multikinase IPMK-1 regulates development through IP3/calcium signaling in Caenorhabditis elegans.Semantic proximity Read ↗

Synaptic defects and compensatory regulation of inositol metabolism in inositol polyphosphate 1-phosphatase mutants.Semantic proximity Read ↗

Phosphatidylinositol 4,5-bisphosphate Impacts Extracellular Vesicle Shedding from <i>C. elegans</i> Ciliated Sensory NeuronsSemantic proximity Read ↗

PIKI-1, a class II phosphatidylinositol 3-kinase, functions in endocytic traffickingSemantic proximity Read ↗

Inositol 1,4,5-trisphosphate signaling regulates mating behavior in Caenorhabditis elegans males.Semantic proximity Read ↗

PIKI-1, a class II PI 3-kinase, functions in endocytic trafficking.Semantic proximity Read ↗

The P-type ATPase CATP-1 is a novel regulator of C. elegans developmental timing that acts independently of its predicted pump function.Semantic proximity Read ↗

The mood stabilizer valproate inhibits both inositol- and diacylglycerol-signaling pathways in Caenorhabditis elegans.Semantic proximity Read ↗

IPPK-1 and IP6 contribute to ventral nerve cord assembly in C. elegans.Semantic proximity Read ↗

A chemical-genetic strategy reveals distinct temporal requirements for SAD-1 kinase in neuronal polarization and synapse formation.Semantic proximity Read ↗

Neuroendocrine control of synaptic transmission by PHAC-1 in <i>C. elegans</i>Semantic proximity Read ↗

Neuronal transcriptome analyses reveal novel neuropeptide modulators of excitation and inhibition imbalance in <i>C. elegans</i>Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.