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Article

Thioredoxin-independent regulation of metabolism by the alpha-arrestin proteins.

The Journal of biological chemistry - 11 Sept 2009

Patwari Parth, Chutkow William A, Cummings Kiersten, Verstraeten Valerie L R M, Lammerding Jan, Schreiter Eric R, Lee Richard T

Abstract excerpt

Thioredoxin-interacting protein (Txnip), originally characterized as an inhibitor of thioredoxin, is now known to be a critical regulator of glucose metabolism in vivo. Txnip is a member of the alpha-arrestin protein family; the alpha-arrestins are related to the classical beta-arrestins and visual arrestins. Txnip is the only alpha-arrestin known to bind thioredoxin, and it is not known whether the metabolic...

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Identifiers

PMID: 19605364
DOI: 10.1074/jbc.M109.018093
PMCID: PMC2757204

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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