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Article

Phenotype changes and impaired function of dendritic cell subsets in patients with sepsis: a prospective observational analysis.

Critical care (London, England) - 1 Jan 2009

Poehlmann Holger, Schefold Joerg C, Zuckermann-Becker Heidrun, Volk Hans-Dieter, Meisel Christian

Abstract excerpt

INTRODUCTION: Patients with sepsis often demonstrate severely impaired immune responses. The hallmark of this state of immunoparalysis is monocytic deactivation characterized by decreased human leukocyte antigen (HLA)-DR expression and reduced production of proinflammatory cytokines. Recently, diminished numbers of dendritic cells (DCs) were reported in patients with sepsis. However, little is known about DC...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 19604380
DOI: 10.1186/cc7969
PMCID: PMC2750167

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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