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Article

Polymicrobial sepsis induces divergent effects on splenic and peritoneal dendritic cell function in mice.

Shock (Augusta, Ga.) - 1 Aug 2004

Ding Yanli, Chung Chun-Shiang, Newton Sarah, Chen Yaping, Carlton Stacey, Albina Jorge E, Ayala Alfred

Abstract excerpt

Dendritic cells (DCs) are professional antigen-presenting cells that act as sentinels in the cell-mediated response against invading pathogens associated with septic challenge. The purpose of the present study was to determine whether there is a loss of dendritic cells and/or changes in function of these cells in septic mice. Here we report that the number of DCs, in both spleen and peritoneum, decreased over 24...

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Identifiers

PMID: 15257086
DOI: 10.1097/01.shk.0000131194.80038.3f
PMCID: PMC2253681

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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