Article
Expression of monocyte human leukocyte antigen-DR in relation with sepsis severity and plasma mediators.
Minerva anestesiologica - 1 Sept 2009
Payen D, Faivre V, Lukaszewicz A C, Villa F, Goldberg P
Abstract excerpt
AIM: After an initial septic hit, the immune response to a new antigen changes as time progresses, with an unpredictable efficiency. The aim of this study was to characterize the monocyte functional phenotype by HLA-DR expression in septic patients at the onset of sepsis and during recovery in relation to organ failure and plasma mediators. METHODS: Twenty-six patients were analyzed as either single organ failure...
Topics
- Adult
- Aged
- Cytokines
- Female
- HLA-DR Antigens
- Humans
- Hydrocortisone
- Immunosuppressive Agents
- Inflammation Mediators
- Leukocyte Count
- Lipopolysaccharides
- Male
- Middle Aged
- Phenotype
- Sepsis
- Young Adult
