Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illness

6 Dec 2024

Abstract excerpt

Introduction: Immunoparalysis is a state of immune dysfunction characterized by a marked reduction in the immune system's responsiveness, often observed following severe infections, trauma, or critical illness. This study aimed to perform a longitudinal assessment of immune function over the initial two weeks following the onset of sepsis and critical illness. Methods: We compared ex vivo-stimulated cytokine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Immune Response and Inflammation
Share to Neonatal and Maternal Infections
Share to Sepsis Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39712015
DOI: 10.3389/fimmu.2024.1498974

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Time-dependent variation in immunoparalysis biomarkers among patients with sepsis and critical illnessPMID 39712015Read ↗

Immune profiling demonstrates a common immune signature of delayed acquired immunodeficiency in patients with various etiologies of severe injurySemantic proximity Read ↗

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients.Semantic proximity Read ↗

Expression of monocyte human leukocyte antigen-DR in relation with sepsis severity and plasma mediators.Semantic proximity Read ↗

Comprehensive analysis of lymphocyte subsets and transcriptome profiles in sepsis-induced acute respiratory distress syndrome: a prospective, observational studySemantic proximity Read ↗

The Pivotal Role of Immune Functional Assays in Deciphering Immune Function AlterationsSemantic proximity Read ↗

A Whole Blood Enzyme-Linked Immunospot Assay for Functional Immune Endotyping of Septic Patients.Semantic proximity Read ↗

Unique lymphocyte transcriptomic profiles in septic patients with chronic critical illnessSemantic proximity Read ↗

Adverse Long-Term Outcomes and an Immune Suppressed Endotype in Sepsis Patients with Reduced Interferon-γ ELISpot: A Multicenter, Prospective Observational StudySemantic proximity Read ↗

Immune Profiling Panel: a proof of concept study of a new multiplex molecular tool to assess the immune status of critically-ill patientsSemantic proximity Read ↗

Longitudinal Immune Profiling in Sepsis Reveals Transient Expansion of a CD14<sup>+</sup>Monocyte State and Persistent T Cell SuppressionSemantic proximity Read ↗

Peripheral immune phenotyping identifies an immunosuppressed sepsis endotype with potential relevance for immune stratification.Semantic proximity Read ↗

Quantitative Real-Time Polymerase Chain Reaction Measurement of HLA-DRA Gene Expression in Whole Blood Is Highly Reproducible and Shows Changes That Reflect Dynamic Shifts in Monocyte Surface HLA-DR Expression during the Course of SepsisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.