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Article

Monocyte Trajectories Endotypes Are Associated With Worsening in Septic Patients.

Frontiers in immunology - 1 Jan 2021

Bodinier Maxime, Peronnet Estelle, Brengel-Pesce Karen, Conti Filippo, Rimmelé Thomas, Textoris Julien, Vedrine Christophe, Quemeneur Laurence, Griffiths Andrew D, Tan Lionel K, Venet Fabienne, Maucort-Boulch Delphine, Monneret Guillaume

Abstract excerpt

Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection. The immune system plays a key role in sepsis onset and remains dysregulated over time in a heterogeneous manner. Here, we decipher the heterogeneity of the first week evolution of the monocyte HLA-DR (mHLA-DR) surface protein expression in septic patients, a key molecule for adaptive immunity onset. We found and...

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Identifiers

PMID: 34912347
DOI: 10.3389/fimmu.2021.795052
PMCID: PMC8667763

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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