Article
Analysis of upstream regulatory regions required for the activities of two promoters of the rat aldolase A gene.
FEBS letters - 4 Nov 1991
Joh K, Takano K, Mukai T, Hori K
Abstract excerpt
Rat aldolase A gene has 2 promoters with different tissue specificities (M- and AH promoters). The M promoter is active only in adult skeletal muscle and induced during myogenesis, whereas the AH promoter is active ubiquitously in many tissues, including various cancer cells. Regulatory sequences for these promoters were investigated through assays for transient expression after introduction into myogenic and...
Topics
- Animals
- Base Sequence
- Chick Embryo
- Chloramphenicol O-Acetyltransferase
- DNA
- Enhancer Elements, Genetic
- Fructose-Bisphosphate Aldolase
- Gene Expression
- Molecular Sequence Data
- Muscles
- Mutation
