Article
Fast-muscle-specific DNA-protein interactions occurring in vivo at the human aldolase A M promoter are necessary for correct promoter activity in transgenic mice.
Molecular and cellular biology - 1 Jan 1996
Salminen M, López S, Maire P, Kahn A, Daegelen D
Abstract excerpt
The human aldolase A tissue-specific M promoter (pM) has served as a model system for identifying pathways that lead to fast-muscle-specialized expression. The current study has delimited the sequences necessary and sufficient for fast-muscle-specific expression in transgenic mice to a short 209-bp fragment extending from bp -164 to +45 relative to the pM transcription start site. Genomic footprinting methods...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
