Article
Human HMGA2 promoter is coregulated by a polymorphic dinucleotide (TC)-repeat.
Oncogene - 6 Feb 2003
Borrmann Lars, Seebeck B, Rogalla P, Bullerdiek J
Abstract excerpt
HMGA proteins are thought to be causally involved in the progression of different diseases, including benign and malignant tumors, obesity, arteriosclerosis, and restenosis. As HMGA proteins are architectural transcription factors, their binding to DNA leads to changes in DNA-conformation modulating the environment for the assembly and function of transcriptional complexes, thus influencing the expression of a...
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