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Article

Multiple pathways regulate 3' overhang generation at S. cerevisiae telomeres.

Molecular cell - 10 Jul 2009

Bonetti Diego, Martina Marina, Clerici Michela, Lucchini Giovanna, Longhese Maria Pia

Abstract excerpt

Generation of 3' G strand overhangs at telomere ends may play a role in regulating telomerase action and occurs by still unclear mechanisms. We show by an inducible short telomere assay that Sae2 and the Sgs1 RecQ helicase control two distinct but partially complementary pathways for nucleolytic processing of S. cerevisiae telomeres, with Sae2 function requiring its serine 267 phosphorylation. No processing...

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Identifiers

PMID: 19595717
DOI: 10.1016/j.molcel.2009.05.015

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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