Differential conservation of nucleotides and conservation/mutation correlations between nucleotides, with special reference to CXC 1 and 4 and FP receptors involved in immune regulation.

Abstract excerpt

Random mutations of the first nucleotide of a coding triplet alter the hydropathic character of 27 % of the hydrophobic amino acids and of 23 % of the hydrophilic amino acids, while random mutations of the second nucleotide alter the hydropathic character of 82 % of the hydrophobic amino acids and of 47 % of the hydrophilic amino acids. In cases of a change of the hydropathic character, a second random mutation...

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