Article
Formyl peptide receptors on immune and nonimmune cells: analysis of sequence conservation in FPR genes.
Immunopharmacology and immunotoxicology - 1 Jan 2007
Panaro M A, Acquafredda A, Sisto M, Lisi S, Calvello R, Mitolo C I, Cianciulli A, Mitolo V
Abstract excerpt
Formyl peptides are oligopeptides released by Gram-negative bacteria. So far, specific formyl peptide receptors (FPRs) have been described in mammals only. FPRs are seven-transmembrane G-coupled molecules and make up a relatively homogeneous group, although exhibiting different levels of affinity for the ligands. We examined the patterns of conservation/mutation within the FPR group of genes, as studied in 16...
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