Article
Nonrandom distribution of cryptic repeating triplets of purines and pyrimidines (RNY)(n) in gp120 of HIV Type1.
AIDS research and human retroviruses - 1 May 2012
De Crignis Elisa, Guglietta Silvia, Foley Brian T, Negroni Matteo, Di Narzo Antonio Fabio, Waelti Da Costa Vreneli, Cavassini Matthias, Bart Pierre-Alexandre, Pantaleo Giuseppe, Graziosi Cecilia
Abstract excerpt
We have analyzed purine (R) and pyrimidine (Y) codon patterns in variable and constant regions of HIV-1 gp120 in seven patients infected with different HIV-1 subtypes and naive to antiretroviral therapy. We have calculated the relative frequency of each in-frame codon RNY, YNR, RNR, and YNY (N=any nucleotide) in variable and constant regions of gp120, in the sequence within indels and at indels' flanking sites....
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