Article
Mutation, selection and the amino acid hydropathic character: a study on receptor genes involved in immune and non-immune functions.
Endocrine, metabolic & immune disorders drug targets - 1 Mar 2009
Panaro Maria A, Sisto Margherita, Mitolo Carlo I, Cianciulli Antonia, Mitolo Vincenzo
Abstract excerpt
In some mRNA sequences, namely those of formyl peptide receptors and chemokine CXC receptors 4, it has been observed that the second nucleotide (nt) of the coding triplets is significantly more highly conserved than the first nt and the correlation between the conservation indexes of the first two nt is positive and significantly higher than the "basic" correlation usually found between adjacent nt. A theoretical...
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