Article
Mutation patterns in the chemokine CXC receptor 4 gene subfamily.
Immunopharmacology and immunotoxicology - 1 Jan 2008
Panaro Maria A, Mitolo Carlo I, Acquafredda Angela, Cianciulli Antonia, Lisi Sabrina, Porro Chiara, Mitolo Vincenzo
Abstract excerpt
Six representative CXCR4 mRNAs of fish, amphibia, birds, and mammals were selected to study the pattern of conservation/mutation of the individual nt of the coding sequences. According to an arbitrary conservation index ranging from 1 to 6, the indexes of conservation were: 5.04 for the first nt of coding triplets; 5.34 for the second nt of triplets, and 3.75 for the third nt of triplets. The average conservation...
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