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Article

No association between CYP2C19 genetic polymorphism with treatment remission to antidepressant venlafaxine in Han Chinese population.

Psychiatric genetics - 1 Feb 2020

Zhang Naixing, Ji Lei, Chen Zhixuan, An Lin, Ren Decheng, Bi Yan, Guo Zhenming, Yuan Ruixue, Yuan Fan, Dong Zaiquan, Yin Li, Sun Xueli, Yang Fengping, Li Xingwang, Yu Tao, He Lin, Shi Lei, He Guang

Abstract excerpt

OBJECTIVE: Major depressive disorder (MDD) is a global mental health problem. As a serotonin-noradrenaline reuptake inhibitor (SNRI), the antidepressant venlafaxine is used to alleviate MDD clinically. Recent research has shown that Cytochrome P450 (CYP) enzymes affect venlafaxine efficacy by mediating its metabolism. The present study investigates genetic polymorphisms of cytochrome P450 family 2 subfamily C...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31842058
DOI: 10.1097/YPG.0000000000000246

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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