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Article

Genetic differences in cytochrome P450 enzymes and antidepressant treatment response.

Journal of psychopharmacology (Oxford, England) - 1 Feb 2014

Hodgson Karen, Tansey Katherine, Dernovsek Mojca Zvezdana, Hauser Joanna, Henigsberg Neven, Maier Wolfgang, Mors Ole, Placentino Anna, Rietschel Marcella, Souery Daniel, Smith Rebecca, Craig Ian W, Farmer Anne E, Aitchison Katherine J, Belsey Sarah, Belsy Sarah, Davis Oliver S P, Uher Rudolf, McGuffin Peter

Abstract excerpt

AIMS: Antidepressant response varies between patients, possibly due to differences in the rate cytochrome P450 enzymes metabolise antidepressants into inactive compounds. Drug metabolism rates are influenced by common variants in the genes encoding these enzymes. However, it remains unclear wheth...

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Identifiers

PMID: 24257813
DOI: 10.1177/0269881113512041

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-24257813-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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