Article
Genetic factors regulate the rise in blood pressure in F2 generation crossed between stroke-prone spontaneously hypertensive rats and Wistar-Kyoto rats.
Clinical and experimental pharmacology & physiology - 1 Sept 1991
Ikeda K, Nara Y, Nabica T, Fujimoto A, Endo J, Ishino H, Yamori Y
Abstract excerpt
1. There was no significant difference between the systolic blood pressure (SBP) of offspring derived from SHRSP mother and WKY father and the SBP of offspring derived from WKY mother and SHRSP father at the developing stage (5-13 weeks of age). 2. The degree of genetic determinations of SBP in stroke-prone spontaneously hypertensive rat (SHRSP) at 5, 7, 10 and 13 weeks of age, determined by genetic crosses...
Topics
- Animals
- Blood Pressure
- Female
- Genotype
- Heterozygote
- Hypertension
- Longitudinal Studies
- Male
- Rats
- Rats, Inbred SHR
- Rats, Inbred WKY
