Article
Genetic and maternal influences in rat models of spontaneous and salt-induced hypertension.
Developmental psychobiology - 1 Nov 1991
Adams N, Blizard D A
Abstract excerpt
Genetic and maternal influences on hypertension were studied by comparing the SHR and SS/Jr inbred rat strains and their reciprocal F1 hybrids under identical conditions. When raised on a low salt (LS) diet (0.3% NaCl), SHR rats had higher systolic blood pressure (SBP) than SS/Jr rats by 9 weeks of age. Direct recordings from freely moving rats at 18-24 weeks confirmed this difference. Placement on a high salt...
Topics
- Animals
- Blood Pressure
- Body Weight
- Crosses, Genetic
- Female
- Heart Rate
- Hypertension
- Male
- Phenotype
- Rats
- Rats, Inbred SHR
- Social Environment
