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Article

Localization of Type 1 Diabetes susceptibility in the ancestral haplotype 18.2 by high density SNP mapping.

Genomics - 1 Oct 2009

Santiago Jose Luis, Li Wentian, Lee Annette, Martinez Alfonso, Chandrasekaran Alamelu, Fernandez-Arquero Miguel, Khalili Houman, de la Concha Emilio G, Urcelay Elena, Gregersen Peter K

Abstract excerpt

Previous studies have suggested that the ancestral haplotype 18.2 (AH18.2) carries additional susceptibility gene to Type 1 Diabetes (T1D) on the Major Histocompatibility Complex (MHC). We analyzed 10 DR3/TNFa1b5 homozygous subjects in order to establish the conservation of the AH18.2 and then compared this conserved region with other DR3 haplotype, the AH8.1. The Illumina's HumanHap550 Bead chip was used to...

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Source

Identifiers

PMID: 19591919
DOI: 10.1016/j.ygeno.2009.06.007

Genes

DDR1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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