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Article

A gene conferring susceptibility to type 2 diabetes in conjunction with obesity is located on chromosome 18p11.

Diabetes - 1 Mar 2001

Parker A, Meyer J, Lewitzky S, Rennich J S, Chan G, Thomas J D, Orho-Melander M, Lehtovirta M, Forsblom C, Hyrkkö A, Carlsson M, Lindgren C, Groop L C

Abstract excerpt

Genome-wide nonparametric linkage analysis of 480 sib-pairs affected with type 2 diabetes revealed linkage to a previously unreported susceptibility locus on chromosome 18p11. This result improved with stringent subphenotyping using age- and sex-adjusted BMI, ultimately reaching a logarithm of odds of 3.82 (allele sharing 0.6654) at a point between markers D18S976 and D18S391 when the most obese 20% of the sample...

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Identifiers

PMID: 11246890
DOI: 10.2337/diabetes.50.3.675

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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