Article
N-cadherin is required for neural crest remodeling of the cardiac outflow tract.
Developmental biology - 15 Nov 2006
Luo Yang, High Frances A, Epstein Jonathan A, Radice Glenn L
Abstract excerpt
Cardiac neural crest cells undergo extensive cell rearrangements during the formation of the aorticopulmonary septum in the outflow tract. However, the morphogenetic mechanisms involved in this fundamental process remain poorly understood. To determine the function of the Ca2+-dependent cell adhesion molecule, N-cadherin, in murine neural crest, we applied the Cre/loxP system and created mouse embryos genetically...
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