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Article

Pinch1 is required for normal development of cranial and cardiac neural crest-derived structures.

Circulation research - 2 Mar 2007

Liang Xingqun, Sun Yunfu, Schneider Jurgen, Ding Jian-Hua, Cheng Hongqiang, Ye Maoqing, Bhattacharya Shoumo, Rearden Ann, Evans Sylvia, Chen Ju

Abstract excerpt

Pinch1, an adaptor protein composed of 5 LIM domains, has been suggested to play an important role in multiple cellular processes. We found that Pinch1 is highly expressed in neural crest cells and their derivatives. To examine the requirement for Pinch1 in neural crest development, we generated neural crest conditional Pinch1 knockout mice using the Wnt1-Cre/loxP system. Neural crest conditional Pinch1 mutant...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Gene Expression Regulation, Developmental

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Source

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Identifiers

PMID: 17272814
DOI: 10.1161/01.RES.0000259041.37059.8c
PMCID: PMC5837278

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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