Article
Temporal-spatial ablation of neural crest in the mouse results in cardiovascular defects.
Developmental dynamics : an official publication of the American Association of Anatomists - 1 Jan 2008
Porras Diego, Brown Christopher B
Abstract excerpt
Neural crest cells are thought to play a critical role in human conotruncal morphogenesis and dysmorphogenesis. Much of our understanding of the contribution of neural crest to cardiovascular patterning comes from ablation and transplantation experiments in avian species. Although fate mapping experiments in mice suggests a conservation of function, the functional requirement for neural crest in cardiovascular...
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