Article
Phenotypic transformation of normal rat kidney cells: a model for studying cellular alterations in oncogenesis.
Critical reviews in oncogenesis - 1 Jan 1991
van Zoelen E J
Abstract excerpt
The growth characteristics of cells in culture change dramatically upon tumorigenic transformation. By the use of selective culture media supplemented with growth factor-inactivated serum, the changes in requirements for externally added polypeptide growth factors can readily be assessed. Certain...
Topics
- Animals
- Cell Division
- Cell Line
- Cell Line, Transformed
- Cell Transformation, Neoplastic
- Growth Substances
- Kidney
- Kinetics
- Models, Biological
- Phenotype
- Rats
