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Article

Transforming growth factor-beta enhances the extent of intercellular communication between normal rat kidney cells.

The Journal of biological chemistry - 25 Jun 1991

van Zoelen E J, Tertoolen L G

Abstract excerpt

Normal rat kidney (NRK) cells cultured in the presence of epidermal growth factor are contact-inhibited at confluent densities. In the additional presence of transforming growth factor (TGF)-beta, however, cells undergo phenotypic transformation which is accompanied by a loss of contact inhibition. In this study, we show by means of the fluorescence photobleaching recovery technique and a scrape-loading dye...

Topics

Animals
Cells, Cultured
Epidermal Growth Factor
Extracellular Matrix
Fluorescence Polarization
Hydrogen-Ion Concentration
Intercellular Junctions
Kidney
Phenotype
Rats
Transforming Growth Factor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 2050701

Genes

NRK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2050701-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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