Article
Transforming growth factor-beta enhances the extent of intercellular communication between normal rat kidney cells.
The Journal of biological chemistry - 25 Jun 1991
van Zoelen E J, Tertoolen L G
Abstract excerpt
Normal rat kidney (NRK) cells cultured in the presence of epidermal growth factor are contact-inhibited at confluent densities. In the additional presence of transforming growth factor (TGF)-beta, however, cells undergo phenotypic transformation which is accompanied by a loss of contact inhibition. In this study, we show by means of the fluorescence photobleaching recovery technique and a scrape-loading dye...
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