Article
Family-based association study of the serotonin-2A receptor gene (5-HT2A) and bipolar disorder.
Neuromolecular medicine - 1 Jan 2002
Ni Xingqun, Trakalo Joseph M, Mundo Emanuela, Lee Lisa, Parikh Sagar, Kennedy James L
Abstract excerpt
OBJECTIVES: The serotonin 2A receptor gene (5-HT2A) is of great interest for research in neuropsychiatric disorders based on the observation that various neuroleptic agents and antidepressants bind with relatively high affinity at 5-HT2A receptors, and the fact that the receptor density in platelets tends to increase in depression. To test for the presence of association between 5-HT2A and bipolar disorder (BP),...
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