Article
Genetic variation of the 5-HT2A receptor gene and bipolar affective disorder.
Human genetics - 1 Oct 1997
Gutiérrez B, Bertranpetit J, Collier D, Arranz M J, Vallès V, Guillamat R, Van Os J, Fañanás L
Abstract excerpt
Abnormalities of the serotonergic system have classically been associated with the origin of affective disorders through the biochemical action of therapeutic agents and their role in affective and perceptual states. In the present study, we hypothesized that genetic variation in the 5-hydroxytryptamine (serotonin) type 2A (5-HT2A) receptor gene (HTR2A) might have an effect on the aetiology of bipolar affective...
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