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Article

Assessment of SNP streak statistics using gene drop simulation with linkage disequilibrium.

Genetic epidemiology - 1 Feb 2010

Thomas Alun

Abstract excerpt

We describe methods and programs for simulating the genotypes of individuals in a pedigree at large numbers of linked loci when the alleles of the founders are under linkage disequilibrium. Both simulation and estimation of linkage disequilibrium models are shown to be feasible on a genome wide scale. The methods are applied to evaluate the statistical significance of streaks of loci at which sets of related...

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Identifiers

PMID: 19582786
DOI: 10.1002/gepi.20440
PMCID: PMC2811755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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